phenformin (CHEBI:8064)

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ChEBI Name	phenformin

ChEBI ID	CHEBI:8064

Definition	A member of the class of biguanides that is biguanide in which one of the terminal nitrogen atoms is substituted by a 2-phenylethyl group. It was used as an anti-diabetic drug but was later withdrawn from the market due to potential risk of lactic acidosis.

Stars	This entity has been manually annotated by the ChEBI Team.

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Formula

C10H15N5

Net Charge

Average Mass

205.265

Monoisotopic Mass

205.13275

InChI

InChI=1S/C10H15N5/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H6,11,12,13,14,15)

InChIKey

ICFJFFQQTFMIBG-UHFFFAOYSA-N

SMILES

NC(=N)NC(=N)NCCC1=CC=CC=C1

Roles Classification
Application(s):	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan. hypoglycemic agent A drug which lowers the blood glucose level. (via biguanides )

ChEBI Ontology
Outgoing	phenformin (CHEBI:8064) has functional parent biguanide (CHEBI:3095) phenformin (CHEBI:8064) has role antineoplastic agent (CHEBI:35610) phenformin (CHEBI:8064) has role geroprotector (CHEBI:176497) phenformin (CHEBI:8064) has role hypoglycemic agent (CHEBI:35526) phenformin (CHEBI:8064) is a biguanides (CHEBI:53662)

IUPAC Name

N-(2-phenylethyl)imidodicarbonimidic diamide

Synonym	Source
DBI	KEGG COMPOUND

Last Modified

28 October 2021