CHEBI:8066 - phenindione

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ChEBI Name phenindione ChEBI ID CHEBI:8066 Stars This entity has been manually annotated by the ChEBI Team. Supplier Information ZINC000013831540 Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Oxycodone, sold under the brand name Roxicodone and OxyContin (which is the extended-release form) among others, is a semi-synthetic opioid used medically for the treatment of moderate to severe pain. It is highly addictive and is a commonly abused drug. It is usually taken by mouth, and is available in immediate-release and controlled-release formulations. Onset of pain relief typically begins within fifteen minutes and lasts for up to six hours with the immediate-release formulation. In the United Kingdom, it is available by injection. Combination products are also available with paracetamol (acetaminophen), ibuprofen, naloxone, naltrexone, and aspirin. Common side effects include euphoria, constipation, nausea, vomiting, loss of appetite, drowsiness, dizziness, itching, dry mouth, and sweating. Side effects may also include addiction and dependence, substance abuse, irritability, depression or mania, delirium, hallucinations, hypoventilation, gastroparesis, bradycardia, and hypotension. Those allergic to codeine may also be allergic to oxycodone. Use of oxycodone in early pregnancy appears relatively safe. Opioid withdrawal may occur if rapidly stopped. Oxycodone acts by activating the μ-opioid receptor. When taken by mouth, it has roughly 1.5 times the effect of the equivalent amount of morphine. Oxycodone was originally produced from the opium poppy opiate alkaloid thebaine in 1916 in Germany. One year later, it was used medically for the first time in Germany in 1917. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2022, it was the 60th most commonly prescribed medication in the United States, with more than 11 million prescriptions. A number of abuse-deterrent formulations are available, such as in combination with naloxone or naltrexone. Read full article at Wikipedia Formula C15H10O2 Net Charge 0 Average Mass 222.23870 Monoisotopic Mass 222.06808 InChI InChI=1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H InChIKey NFBAXHOPROOJAW-UHFFFAOYSA-N SMILES O=C1C(C(=O)c2ccccc12)c1ccccc1 Roles Classification Application(s): anticoagulant An agent that prevents blood clotting. View more via ChEBI Ontology ChEBI Ontology Outgoing phenindione (CHEBI:8066) has parent hydride indane (CHEBI:37911) phenindione (CHEBI:8066) has role anticoagulant (CHEBI:50249) phenindione (CHEBI:8066) is a β-diketone (CHEBI:67265) phenindione (CHEBI:8066) is a aromatic ketone (CHEBI:76224) IUPAC Name 2-phenyl-1H-indene-1,3(2H)-dione INNs Sources fenindiona ChemIDplus phenindione ChemIDplus phénindione ChEBI phenindionum ChemIDplus Synonyms Sources 2-phenyl-1,3(2H)-Indenedione NIST Chemistry WebBook 2-phenyl-1,3-diketohydrindene NIST Chemistry WebBook 2-Phenyl-1,3-indandione KEGG COMPOUND Phenindione KEGG COMPOUND PID ChemIDplus Manual Xrefs Databases 2130 DrugCentral C07584 KEGG COMPOUND D08354 KEGG DRUG DB00498 DrugBank LSM-5784 LINCS Phenindione Wikipedia View more database links Registry Numbers Types Sources 1911699 Beilstein Registry Number Beilstein 83-12-5 CAS Registry Number ChemIDplus 83-12-5 CAS Registry Number NIST Chemistry WebBook Last Modified 22 February 2017