phenobarbital sodium (CHEBI:8070)

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ChEBI Name	phenobarbital sodium

ChEBI ID	CHEBI:8070

Definition	A barbiturate that is the sodium salt of phenobarbital (barbituric acid substituted at C-5 by ethyl and phenyl groups).

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formulae

C12H11N2NaO3
C12H11N2O3.Na

Net Charge

Average Mass

254.21710

Monoisotopic Mass

254.06674

InChI

InChI=1S/C12H12N2O3.Na/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16;/h3-7H,2H2,1H3,(H2,13,14,15,16,17);/q;+1/p-1

InChIKey

WRLGYAWRGXKSKG-UHFFFAOYSA-M

SMILES

[Na+].CCC1(C(=O)NC([O-])=NC1=O)c1ccccc1

Roles Classification
Biological Role(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via barbiturates )

Application(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via barbiturates )

ChEBI Ontology
Outgoing	phenobarbital sodium (CHEBI:8070) has part phenobarbital (CHEBI:8069) phenobarbital sodium (CHEBI:8070) is a barbiturates (CHEBI:22693) phenobarbital sodium (CHEBI:8070) is a organic sodium salt (CHEBI:38700)

IUPAC Name

sodium 5-ethyl-4,6-dioxo-5-phenyl-1,4,5,6-tetrahydropyrimidin-2-olate

Synonyms	Sources
5-Ethyl-5-phenylbarbituric acid sodium salt	ChemIDplus
Phenobarbital sodium salt	ChemIDplus
Phenyl-äthyl-barbitursäure natrium	ChemIDplus
Sodium 5-ethyl-5-phenylbarbiturate	ChemIDplus
Sodium luminal	ChemIDplus
Sodium phenobarbital	ChemIDplus
Sodium phenobarbitone	ChemIDplus
Sodium phenobarbiturate	ChemIDplus
Sodium phenylethylbarbiturate	ChemIDplus
Sodium phenylethylmalonylurea	ChemIDplus

Brand Name	Source
Luminal sodium	KEGG DRUG

Last Modified

11 July 2014