CHEBI:84743 - amiloride hydrochloride

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ChEBI Name amiloride hydrochloride
ChEBI ID CHEBI:84743
Definition A hydrochloride obtained by combining amiloride with one molar equivalent of hydrochloric acid.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C6H9Cl2N7O
Net Charge 0
Average Mass 266.08800
Monoisotopic Mass 265.02456
InChI InChI=1S/C6H8ClN7O.ClH/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11;/h(H4,8,9,13)(H4,10,11,14,15);1H
InChIKey ACHKKGDWZVCSNH-UHFFFAOYSA-N
SMILES Cl.NC(=N)NC(=O)c1nc(Cl)c(N)nc1N
Roles Classification
Biological Role(s): sodium channel blocker
An agent that inhibits sodium influx through cell membranes.
Application(s): diuretic
An agent that promotes the excretion of urine through its effects on kidney function.
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ChEBI Ontology
Outgoing amiloride hydrochloride (CHEBI:84743) has part amiloride(1+) (CHEBI:84745)
amiloride hydrochloride (CHEBI:84743) has role diuretic (CHEBI:35498)
amiloride hydrochloride (CHEBI:84743) has role sodium channel blocker (CHEBI:38633)
amiloride hydrochloride (CHEBI:84743) is a hydrochloride (CHEBI:36807)
Incoming amiloride hydrochloride dihydrate (CHEBI:2640) has part amiloride hydrochloride (CHEBI:84743)
IUPAC Name
3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide hydrochloride
Synonyms Sources
Amiloride chloride ChemIDplus
Amiloride HCl ChemIDplus
Amiloride hydrochloride anhydrous ChemIDplus
amiloride monohydrochloride ChEBI
N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide monohydrochloride ChemIDplus
Manual Xrefs Databases
Amiloride Wikipedia
DB00594 DrugBank
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Registry Numbers Types Sources
2016-88-8 CAS Registry Number ChemIDplus
4038903 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
23767356 PubMed citation Europe PMC
24771053 PubMed citation Europe PMC
Last Modified
11 February 2015