CHEBI:177197 - L-803087

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ChEBI Name L-803087 ChEBI ID CHEBI:177197 Definition A fluoroindole that is 1H-indole substituted by phenyl, 4-{[(2S)-5-carbamimidamido-1-methoxy-1-oxopentan-2-yl]amino}-4-oxobutyl, fluoro and fluoro groups at positions 2, 3, 5 and 7, respectively. It is a selective nonpeptidic agonist of the somatostatin subtype-4 (SST4) receptor with Ki of 0.7 nM. Stars This entity has been manually annotated by the ChEBI Team. Submitter Sandra Orchard Secondary ChEBI IDs CHEBI:91648 Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Formula C25H29F2N5O3 Net Charge 0 Average Mass 485.536 Monoisotopic Mass 485.22385 InChI InChI=1S/C25H29F2N5O3/c1-35-24(34)20(10-6-12-30-25(28)29)31-21(33)11-5-9-17-18-13-16(26)14-19(27)23(18)32-22(17)15-7-3-2-4-8-15/h2-4,7-8,13-14,20,32H,5-6,9-12H2,1H3,(H,31,33)(H4,28,29,30)/t20-/m0/s1 InChIKey OPNMQSFIGUSHDH-FQEVSTJZSA-N SMILES COC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCC1=C(NC2=C1C=C(F)C=C2F)C1=CC=CC=C1 Roles Classification Biological Role(s): somatostatin receptor agonist An agonist that binds to and activates somatostatin receptors. View more via ChEBI Ontology ChEBI Ontology Outgoing L-803087 (CHEBI:177197) has role somatostatin receptor agonist (CHEBI:177023) L-803087 (CHEBI:177197) is a L-arginine derivative (CHEBI:83965) L-803087 (CHEBI:177197) is a benzenes (CHEBI:22712) L-803087 (CHEBI:177197) is a fluoroindole (CHEBI:131960) L-803087 (CHEBI:177197) is a guanidines (CHEBI:24436) L-803087 (CHEBI:177197) is a methyl ester (CHEBI:25248) L-803087 (CHEBI:177197) is a phenylindole (CHEBI:48559) L-803087 (CHEBI:177197) is a secondary carboxamide (CHEBI:140325) IUPAC Name methyl N2-[4-(5,7-difluoro-2-phenyl-1H-indol-3-yl)butanoyl]-L-argininate Synonyms Sources L 803087 ChEBI L-803,087 ChEBI L803087 ChEBI methyl (2S)-5-carbamimidamido-2-[4-(5,7-difluoro-2-phenyl-1H-indol-3-yl)butanamido]pentanoate IUPAC N2-[4-(5,7-difluoro-2-phenyl-1H-indol-3-yl)-1-oxobutyl]-L-arginine methyl ester ChEBI Manual Xrefs Databases 4470867 ChemSpider LSM-1482 LINCS View more database links Registry Number Type Source 217480-26-7 CAS Registry Number SUBMITTER Citations Types Sources 10433861 PubMed citation Europe PMC 11087999 PubMed citation Europe PMC 12372020 PubMed citation Europe PMC 14667213 PubMed citation Europe PMC 15380378 PubMed citation Europe PMC 15733093 PubMed citation Europe PMC 16081634 PubMed citation Europe PMC 18390640 PubMed citation Europe PMC 18521573 PubMed citation Europe PMC 18766330 PubMed citation Europe PMC 19623609 PubMed citation Europe PMC 19811607 PubMed citation Europe PMC 20573967 PubMed citation Europe PMC 20826222 PubMed citation Europe PMC 21854790 PubMed citation Europe PMC 26631476 PubMed citation Europe PMC 30675231 PubMed citation Europe PMC 9784130 PubMed citation Europe PMC Last Modified 05 August 2021