CHEBI:9362 - suprofen

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name suprofen
ChEBI ID CHEBI:9362
Definition An aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:193117
Supplier Information No supplier information found for this compound.
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Formula C14H12O3S
Net Charge 0
Average Mass 260.30800
Monoisotopic Mass 260.05072
InChI InChI=1S/C14H12O3S/c1-9(14(16)17)10-4-6-11(7-5-10)13(15)12-3-2-8-18-12/h2-9H,1H3,(H,16,17)
InChIKey MDKGKXOCJGEUJW-UHFFFAOYSA-N
SMILES CC(C(O)=O)c1ccc(cc1)C(=O)c1cccs1
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes.
drug allergen
Any drug which causes the onset of an allergic reaction.
Application(s): non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
antirheumatic drug
A drug used to treat rheumatoid arthritis.
peripheral nervous system drug
A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system.
drug allergen
Any drug which causes the onset of an allergic reaction.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing suprofen (CHEBI:9362) has role antirheumatic drug (CHEBI:35842)
suprofen (CHEBI:9362) has role drug allergen (CHEBI:88188)
suprofen (CHEBI:9362) has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor (CHEBI:35544)
suprofen (CHEBI:9362) has role non-narcotic analgesic (CHEBI:35481)
suprofen (CHEBI:9362) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
suprofen (CHEBI:9362) has role peripheral nervous system drug (CHEBI:49110)
suprofen (CHEBI:9362) is a aromatic ketone (CHEBI:76224)
suprofen (CHEBI:9362) is a monocarboxylic acid (CHEBI:25384)
suprofen (CHEBI:9362) is a thiophenes (CHEBI:26961)
IUPAC Name
2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acid
INNs Sources
suprofen ChemIDplus
suprofene ChemIDplus
suprofenum ChemIDplus
Synonyms Sources
(±)-2-(p-(2-thenoyl)phenyl)propionic acid ChemIDplus
2-(4-(2-Thenoyl)phenyl)propionsäure ChemIDplus
2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid ChEMBL
4-(2-Thenoyl)hydratropsäure ChemIDplus
α-methyl-4-(2-thienylcarbonyl)benzeneacetic acid ChemIDplus
p-2-thenoylhydratropic acid ChemIDplus
PROFENAL ChEMBL
SUTOPROFEN ChEMBL
Manual Xrefs Databases
2546 DrugCentral
C07320 KEGG COMPOUND
D00452 KEGG DRUG
DB00870 DrugBank
DE2353357 Patent
LSM-4406 LINCS
Suprofen Wikipedia
US4035376 Patent
View more database links
Registry Numbers Types Sources
1430606 Reaxys Registry Number Reaxys
40828-46-4 CAS Registry Number KEGG COMPOUND
Citations Waiting for Citations
Last Modified
12 March 2019