Metrifonate (INN) or trichlorfon (USAN) is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into the active agent dichlorvos.
It is used as an insecticide.
According to the US Environmental Protection Agency trichlorfon has been used on golf course turf, home lawns, non-food contact areas of food and meat processing plants, ornamental shrubs and plants, and ornamental and baitfish ponds. Used to control caterpillars, white grubs, mole crickets, cattle lice, sod webworms, leaf miners, stink bugs, flies, ants, cockroaches, earwigs, crickets, diving beetle, water scavenger beetle, water boatman backswimmer, water scorpions, giant water bugs and pillbugs. After reregistration, a number of its uses were voluntarily restricted, and currently, it is used in nonfood areas to control flies, roaches, and ants among other pests. Outdoors it is used on ornamental plants, golf courses, and lawn grass to treat lepidopteran larvae pests, it is also used to treat flies in animal husbandry in areas that are not accessible to animals, it also used to control harvester ants.
It can be used to treat schistosomiasis caused by Schistosoma haematobium, but is no longer commercially available.
It has been proposed for use in treatment of Alzheimer's disease, but use for that purpose is not currently recommended. |
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InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13) |
REEQLXCGVXDJSQ-UHFFFAOYSA-N |
OC(=O)COc1nc(Cl)c(Cl)cc1Cl |
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environmental contaminant
Any minor or unwanted substance introduced into the environment that can have undesired effects.
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
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xenobiotic
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
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herbicide
A substance used to destroy plant pests.
agrochemical
An agrochemical is a substance that is used in agriculture or horticulture.
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View more via ChEBI Ontology
[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid
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659
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PPDB
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C11032
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KEGG COMPOUND
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triclopyr
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Alan Wood's Pesticides
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Triclopyr
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Wikipedia
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View more database links |
225301
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Reaxys Registry Number
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Reaxys
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55335-06-3
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CAS Registry Number
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ChemIDplus
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23688229
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PubMed citation
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Europe PMC
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24623388
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PubMed citation
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Europe PMC
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25309266
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PubMed citation
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Europe PMC
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