AmiGO 2: Term Details for "G2/M transition of mitotic cell cycle" (GO:0000086)

Accession: GO:0000086
Name: G2/M transition of mitotic cell cycle
Ontology: biological_process
Synonyms: mitotic G2/M transition
Alternate IDs: None
Definition: The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex. Source: GOC:mtg_cell_cycle
Comment: None
History: See term history for GO:0000086 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to G2/M transition of mitotic cell cycle (excluding "regulates").; Link to all direct and indirect annotations to G2/M transition of mitotic cell cycle (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for G2/M transition of mitotic cell cycle (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
G2/M transition of mitotic cell cycle	BFO:0000050	mitotic cell cycle (GO:0000278)
G2/M transition of mitotic cell cycle	is_a	cell cycle G2/M phase transition (GO:0044839)
G2/M transition of mitotic cell cycle	is_a	mitotic cell cycle phase transition (GO:0044772)

subject	relation	object
negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)	RO:0002212	G2/M transition of mitotic cell cycle
positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)	RO:0002213	G2/M transition of mitotic cell cycle
regulation of G2/M transition of mitotic cell cycle (GO:0010389)	RO:0002211	G2/M transition of mitotic cell cycle

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