Term Information

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Accession
GO:0000107
Name
imidazoleglycerol-phosphate synthase activity
Ontology
molecular_function
Synonyms
imidazole glycerol phosphate synthase activity, imidazoleglycerol phosphate synthase activity, imidazole-glycerol-phosphate synthase activity, glutamine amidotransferase:cyclase activity
Alternate IDs
None
Definition
Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + aminoimidazole carboxamide ribonucleotide + L-glutamate + 2 H+. Source: RHEA:24793
Comment
None
History
See term history for GO:0000107 at QuickGO
Chem. react.
has participant L-glutamine zwitterion
has participant 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(4-)
has participant hydron
has participant L-glutamate(1-)
has participant D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate(2-)
has participant 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(2-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0000107 from QuickGO

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Parents of imidazoleglycerol-phosphate synthase activity (GO:0000107)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
imidazoleglycerol-phosphate synthase activity [RO:0000057 relation] RO:0000057  L-glutamine zwitterion (CHEBI:58359)
imidazoleglycerol-phosphate synthase activity [is_a relation] is_a  pentosyltransferase activity (GO:0016763)
imidazoleglycerol-phosphate synthase activity [RO:0000057 relation] RO:0000057  5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(4-) (CHEBI:58525)
imidazoleglycerol-phosphate synthase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
imidazoleglycerol-phosphate synthase activity [RO:0000057 relation] RO:0000057  L-glutamate(1-) (CHEBI:29985)
imidazoleglycerol-phosphate synthase activity [RO:0000057 relation] RO:0000057  D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate(2-) (CHEBI:58278)
imidazoleglycerol-phosphate synthase activity [RO:0000057 relation] RO:0000057  5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(2-) (CHEBI:58475)
Children of imidazoleglycerol-phosphate synthase activity (GO:0000107)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
imidazoleglycerol-phosphate synthase complex (GO:0009382) [RO:0002215 relation] RO:0002215  imidazoleglycerol-phosphate synthase activity
MetaCyc
GLUTAMIDOTRANS-RXN
RHEA
24793