Term Information

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Accession
GO:0000215
Name
tRNA 2'-phosphotransferase activity
Ontology
molecular_function
Synonyms
2'-phospho-[ligated tRNA]:NAD+ phosphotransferase activity, 2'-phospho-tRNA:NAD+ phosphotransferase activity, Tpt1, Tpt1p, yeast 2'-phosphotransferase activity, 2'-phosphotransferase activity
Alternate IDs
GO:0008665
Definition
Catalysis of the reaction: 2'-phospho-[ligated tRNA] + NAD+ = mature tRNA + ADP ribose 1'',2''-phosphate + nicotinamide + H2O. This reaction is the transfer of the splice junction 2-phosphate from ligated tRNA to NAD+ to produce ADP-ribose 1'-2' cyclic phosphate. Source: EC:2.7.1.160, PMID:9148937
Comment
None
History
See term history for GO:0000215 at QuickGO
Chem. react.
has participant NAD(1-)
has participant nucleotide 5'-phosphate(1-) residue
has participant 2'-phospho-nucleotide 5'-phosphate(3-) residue
has participant ADP-alpha-D-ribose 1'',2''-cyclic phosphate(3-)
has participant nicotinamide
Subset
goslim_chembl
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0000215 from QuickGO

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Parents of tRNA 2'-phosphotransferase activity (GO:0000215)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
tRNA 2'-phosphotransferase activity [is_a relation] is_a  phosphotransferase activity, alcohol group as acceptor (GO:0016773)
tRNA 2'-phosphotransferase activity [RO:0000057 relation] RO:0000057  NAD(1-) (CHEBI:57540)
tRNA 2'-phosphotransferase activity [RO:0000057 relation] RO:0000057  nucleotide 5'-phosphate(1-) residue (CHEBI:82883)
tRNA 2'-phosphotransferase activity [RO:0000057 relation] RO:0000057  2'-phospho-nucleotide 5'-phosphate(3-) residue (CHEBI:85027)
tRNA 2'-phosphotransferase activity [is_a relation] is_a  catalytic activity, acting on a tRNA (GO:0140101)
tRNA 2'-phosphotransferase activity [RO:0000057 relation] RO:0000057  ADP-alpha-D-ribose 1'',2''-cyclic phosphate(3-) (CHEBI:76596)
tRNA 2'-phosphotransferase activity [RO:0000057 relation] RO:0000057  nicotinamide (CHEBI:17154)

This term has no children.

EC
2.7.1.160
MetaCyc
2.7.1.160-RXN
RHEA
23324