AmiGO 2: Term Details for "lanosterol synthase activity" (GO:0000250)

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Term Information

Accession: GO:0000250
Name: lanosterol synthase activity
Ontology: molecular_function
Synonyms: 2,3-epoxysqualene-lanosterol cyclase activity, OSC, oxidosqualene-lanosterol cyclase activity, oxidosqualene:lanosterol cyclase activity, (S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming), 2,3-epoxysqualene lanosterol cyclase activity, 2,3-epoxysqualene--lanosterol cyclase activity, 2,3-oxidosqualene-lanosterol cyclase activity, lanosterol 2,3-oxidosqualene cyclase activity, oxidosqualene--lanosterol cyclase activity, squalene 2,3-epoxide:lanosterol cyclase activity, squalene-2,3-oxide-lanosterol cyclase activity, 2,3-oxidosqualene sterol cyclase activity, squalene epoxidase-cyclase activity
Alternate IDs: None
Definition: Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus. Source: RHEA:14621, EC:5.4.99.7
Comment: None
History: See term history for GO:0000250 at QuickGO
Chem. react.: has participant lanosterol; has participant (S)-2,3-epoxysqualene
Subset: None
Related: Link to all genes and gene products annotated to lanosterol synthase activity (excluding "regulates").; Link to all direct and indirect annotations to lanosterol synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for lanosterol synthase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016853 isomerase activity
GO:0016866 intramolecular transferase activity
GO:0031559 oxidosqualene cyclase activity
GO:0000250 lanosterol synthase activity

Parents of lanosterol synthase activity (GO:0000250)

subject	relation	object
lanosterol synthase activity	RO:0000057	lanosterol (CHEBI:16521)
lanosterol synthase activity	RO:0000057	(S)-2,3-epoxysqualene (CHEBI:15441)
lanosterol synthase activity	is_a	oxidosqualene cyclase activity (GO:0031559)

This term has no children.

EC: 5.4.99.7
KEGG_REACTION: R03199
MetaCyc: LANOSTEROL-SYNTHASE-RXN
Reactome: R-HSA-191366
RHEA: 14621