AmiGO 2: Term Details for "THO complex" (GO:0000347)

Accession: GO:0000347
Name: THO complex
Ontology: cellular_component
Synonyms: None
Alternate IDs: None
Definition: The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits. Source: GOC:krc, PMID:16983072, PMID:11979277, PMID:11060033
Comment: None
History: See term history for GO:0000347 at QuickGO
Chem. react.: None
Subset: goslim_pir
Related: Link to all genes and gene products annotated to THO complex (excluding "regulates").; Link to all direct and indirect annotations to THO complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for THO complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
THO complex	is_a	nuclear protein-containing complex (GO:0140513)

subject	relation	object
THO complex part of transcription export complex (GO:0000445)	is_a	THO complex
nucleoplasmic THO complex (GO:0000446)	is_a	THO complex

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