Obsolete Term Information

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Accession
GO:0000364
Name
obsolete second U2-type spliceosomal transesterification activity
Ontology
molecular_function
Synonyms
second U2-type spliceosomal transesterification activity, 3'-splice site cleavage, exon ligation
Alternate IDs
None
Definition
OBSOLETE. Catalysis of the second transesterification reaction of U2-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins. Source: GOC:krc, ISBN:0879695897
Comment
This term was made obsolete because the activities used in the U2- and U12-type complexes are the same. The cellular component ontology should (and does) represent the two different complexes, but the molecular function ontology should not.
replaced by: GO:0000386
History
See term history for GO:0000364 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.