Term Information

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Accession
GO:0000372
Name
Group I intron splicing
Ontology
biological_process
Synonyms
mRNA splicing
Alternate IDs
None
Definition
The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize). Source: GOC:krc, PMID:11377794
Comment
Note that Group I introns are known to be found in a number of places: rRNA, mRNA, and tRNA in organelles of fungi, plants, and protists; tRNA and mRNA of bacteria and bacteriophage; rRNA of protists and fungi; and occasionally in mRNA of animal mitochondria (e.g. sea anemone).
History
See term history for GO:0000372 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of Group I intron splicing (GO:0000372)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Group I intron splicing [is_a relation] is_a  RNA splicing, via transesterification reactions with guanosine as nucleophile (GO:0000376)
Children of Group I intron splicing (GO:0000372)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
bI3 intron splicing complex (GO:0106392) [RO:0002216 relation] RO:0002216  Group I intron splicing
bI4 intron splicing complex (GO:0106391) [RO:0002216 relation] RO:0002216  Group I intron splicing
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