AmiGO 2: Term Details for "RNA splicing, via transesterification reactions" (GO:0000375)

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Term Information

Accession: GO:0000375
Name: RNA splicing, via transesterification reactions
Ontology: biological_process
Synonyms: RNA splicing factor activity, transesterification mechanism, pre-mRNA splicing factor activity, spliceosomal catalysis
Alternate IDs: GO:0031202, GO:0000385
Definition: Splicing of RNA via a series of two transesterification reactions. Source: GOC:krc
Comment: Note that nuclear mRNA, Group I, Group II, and Group III introns are all spliced by a series of two transesterification reactions that occur within the RNA itself, or between two RNAs in trans splicing. Some of these require one or more proteins to stabilize the catalytic conformation, while others are autocatalytic. Note that tRNA introns are spliced by a different catalytic mechanism.
History: See term history for GO:0000375 at QuickGO
Chem. react.: None
Subset: goslim_pir
Related: Link to all genes and gene products annotated to RNA splicing, via transesterification reactions (excluding "regulates").; Link to all direct and indirect annotations to RNA splicing, via transesterification reactions (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for RNA splicing, via transesterification reactions (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0044238 primary metabolic process
GO:0008150 biological_process
GO:0009058 biosynthetic process
GO:0043170 macromolecule metabolic process
GO:0008152 metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:0009987 cellular process
GO:0009059 macromolecule biosynthetic process
GO:0090304 nucleic acid metabolic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0141187 nucleic acid biosynthetic process
GO:0016070 RNA metabolic process
GO:0010467 gene expression
GO:0032774 RNA biosynthetic process
GO:0006396 RNA processing
GO:0008380 RNA splicing
GO:0000375 RNA splicing, via transesterification reactions
GO:0000384 first spliceosomal transesterification activity
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
GO:0000376 RNA splicing, via transesterification reactions with guanosine as nucleophile
GO:0000386 second spliceosomal transesterification activity

Parents of RNA splicing, via transesterification reactions (GO:0000375)

subject	relation	object
RNA splicing, via transesterification reactions	is_a	RNA splicing (GO:0008380)

Children of RNA splicing, via transesterification reactions (GO:0000375)

subject	relation	object
RNA splicing, via transesterification reactions with guanosine as nucleophile (GO:0000376)	is_a	RNA splicing, via transesterification reactions
second spliceosomal transesterification activity (GO:0000386)	BFO:0000050	RNA splicing, via transesterification reactions
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)	is_a	RNA splicing, via transesterification reactions
first spliceosomal transesterification activity (GO:0000384)	BFO:0000050	RNA splicing, via transesterification reactions

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