AmiGO 2: Term Details for "mRNA splicing, via spliceosome" (GO:0000398)

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Term Information

Accession: GO:0000398
Name: mRNA splicing, via spliceosome
Ontology: biological_process
Synonyms: nuclear mRNA splicing, via spliceosome, splicing AT-AC intron, splicing GT-AG intron, nuclear mRNA splicing via U12-type spliceosome, nuclear mRNA splicing via U2-type spliceosome, mRNA splicing, pre-mRNA splicing
Alternate IDs: GO:0006374, GO:0006375
Definition: The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. Source: GOC:krc, ISBN:0198506732, ISBN:0879695897
Comment: Note that although the many U12-type introns have the sequence AT-AC at the intron termini, some introns with these terminal sequences are spliced by the U2-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron. Note that although the majority of U2-type introns have the sequence GU-AG at the intron termini, some introns with these terminal sequences are spliced by the U12-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron.
History: See term history for GO:0000398 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to mRNA splicing, via spliceosome (excluding "regulates").; Link to all direct and indirect annotations to mRNA splicing, via spliceosome (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for mRNA splicing, via spliceosome (excluding "regulates").

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GO:0008150 biological_process
GO:0008152 metabolic process
GO:0044237 cellular metabolic process
GO:0009987 cellular process
GO:0006807 nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
GO:0009058 biosynthetic process
GO:0006725 cellular aromatic compound metabolic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0046483 heterocycle metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:0044238 primary metabolic process
GO:0044249 cellular biosynthetic process
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0009059 macromolecule biosynthetic process
GO:0090304 nucleic acid metabolic process
GO:0006396 RNA processing
GO:0010467 gene expression
GO:0016070 RNA metabolic process
GO:0008380 RNA splicing
GO:0016071 mRNA metabolic process
GO:0000375 RNA splicing, via transesterification reactions
GO:0006397 mRNA processing
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
GO:0000398 mRNA splicing, via spliceosome
GO:0000380 alternative mRNA splicing, via spliceosome
GO:0045292 mRNA cis splicing, via spliceosome
GO:0000365 mRNA trans splicing, via spliceosome
GO:0048025 negative regulation of mRNA splicing, via spliceosome
GO:0048026 positive regulation of mRNA splicing, via spliceosome
GO:0048024 regulation of mRNA splicing, via spliceosome
GO:0000245 spliceosomal complex assembly
GO:0000390 spliceosomal complex disassembly
GO:0000393 spliceosomal conformational changes to generate catalytic conformation
GO:0000387 spliceosomal snRNP assembly
GO:0160091 spliceosome-depend formation of circular RNA

Parents of mRNA splicing, via spliceosome (GO:0000398)

subject	relation	object
mRNA splicing, via spliceosome	is_a	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)
mRNA splicing, via spliceosome	is_a	mRNA processing (GO:0006397)

Children of mRNA splicing, via spliceosome (GO:0000398)

subject	relation	object
regulation of mRNA splicing, via spliceosome (GO:0048024)	RO:0002211	mRNA splicing, via spliceosome
spliceosome-depend formation of circular RNA (GO:0160091)	is_a	mRNA splicing, via spliceosome
spliceosomal complex disassembly (GO:0000390)	BFO:0000050	mRNA splicing, via spliceosome
alternative mRNA splicing, via spliceosome (GO:0000380)	is_a	mRNA splicing, via spliceosome
spliceosomal complex assembly (GO:0000245)	BFO:0000050	mRNA splicing, via spliceosome
spliceosomal conformational changes to generate catalytic conformation (GO:0000393)	BFO:0000050	mRNA splicing, via spliceosome
positive regulation of mRNA splicing, via spliceosome (GO:0048026)	RO:0002213	mRNA splicing, via spliceosome
negative regulation of mRNA splicing, via spliceosome (GO:0048025)	RO:0002212	mRNA splicing, via spliceosome
mRNA cis splicing, via spliceosome (GO:0045292)	is_a	mRNA splicing, via spliceosome
mRNA trans splicing, via spliceosome (GO:0000365)	is_a	mRNA splicing, via spliceosome
spliceosomal snRNP assembly (GO:0000387)	BFO:0000050	mRNA splicing, via spliceosome

mRNA splicing, via spliceosome