AmiGO 2: Term Details for "Prp19 complex" (GO:0000974)

Accession: GO:0000974
Name: Prp19 complex
Ontology: cellular_component
Synonyms: NTC, MOS4-Associated Complex, Prp19/CDC5 complex, nineteen complex
Alternate IDs: None
Definition: A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p. Source: GOC:krc, PMID:19239890, PMID:16540691
Comment: None
History: See term history for GO:0000974 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to Prp19 complex (excluding "regulates").; Link to all direct and indirect annotations to Prp19 complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for Prp19 complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
Prp19 complex	is_a	protein-containing complex (GO:0032991)

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