AmiGO 2: Term Details for "RNA polymerase II transcription regulatory region sequence-specific DNA binding" (GO:0000977)

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Term Information

Accession: GO:0000977
Name: RNA polymerase II transcription regulatory region sequence-specific DNA binding
Ontology: molecular_function
Synonyms: RNA polymerase II regulatory region DNA binding
Alternate IDs: GO:0001012
Definition: Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II. Source: GOC:txnOH
Comment: To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription.
History: See term history for GO:0000977 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to RNA polymerase II transcription regulatory region sequence-specific DNA binding (excluding "regulates").; Link to all direct and indirect annotations to RNA polymerase II transcription regulatory region sequence-specific DNA binding (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for RNA polymerase II transcription regulatory region sequence-specific DNA binding (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0003674 molecular_function
GO:0005488 binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0097159 organic cyclic compound binding
GO:0003690 double-stranded DNA binding
GO:0043565 sequence-specific DNA binding
GO:1990837 sequence-specific double-stranded DNA binding
GO:0001067 transcription regulatory region nucleic acid binding
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
GO:1905636 positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding
GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding
GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
GO:1990378 upstream stimulatory factor complex

Parents of RNA polymerase II transcription regulatory region sequence-specific DNA binding (GO:0000977)

subject	relation	object
RNA polymerase II transcription regulatory region sequence-specific DNA binding	is_a	transcription cis-regulatory region binding (GO:0000976)

Children of RNA polymerase II transcription regulatory region sequence-specific DNA binding (GO:0000977)

subject	relation	object
DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)	BFO:0000051	RNA polymerase II transcription regulatory region sequence-specific DNA binding
regulation of RNA polymerase II regulatory region sequence-specific DNA binding (GO:1903025)	RO:0002211	RNA polymerase II transcription regulatory region sequence-specific DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978)	is_a	RNA polymerase II transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding (GO:0000979)	is_a	RNA polymerase II transcription regulatory region sequence-specific DNA binding
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding (GO:0001162)	is_a	RNA polymerase II transcription regulatory region sequence-specific DNA binding
negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding (GO:1903026)	RO:0002212	RNA polymerase II transcription regulatory region sequence-specific DNA binding
upstream stimulatory factor complex (GO:1990378)	RO:0002215	RNA polymerase II transcription regulatory region sequence-specific DNA binding
positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding (GO:1905636)	RO:0002213	RNA polymerase II transcription regulatory region sequence-specific DNA binding

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