AmiGO 2: Term Details for "RNA polymerase II cis-regulatory region sequence-specific DNA binding" (GO:0000978)

Term Information

Accession: GO:0000978
Name: RNA polymerase II cis-regulatory region sequence-specific DNA binding
Ontology: molecular_function
Synonyms: RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II promoter proximal region sequence-specific DNA binding, RNA polymerase II proximal promoter sequence-specific DNA binding, RNA polymerase II upstream activating sequence (UAS) sequence-specific DNA binding
Alternate IDs: GO:0000980
Definition: Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. Source: GOC:txnOH-2018
Comment: Note that the phrase "upstream activating sequence", or UAS is often used in S. cerevisiae literature to refer to cis-regulatory sequences. In bacteria such as E. coli, the phrase "upstream activating sequence", or UAS is usually a synonym for "enhancer".
History: See term history for GO:0000978 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to RNA polymerase II cis-regulatory region sequence-specific DNA binding (excluding "regulates").; Link to all direct and indirect annotations to RNA polymerase II cis-regulatory region sequence-specific DNA binding (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for RNA polymerase II cis-regulatory region sequence-specific DNA binding (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0003674 molecular_function
GO:0005488 binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0097159 organic cyclic compound binding
GO:0003690 double-stranded DNA binding
GO:0043565 sequence-specific DNA binding
GO:1990837 sequence-specific double-stranded DNA binding
GO:0001067 transcription regulatory region nucleic acid binding
GO:0000976 transcription cis-regulatory region binding
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0035497 cAMP response element binding
GO:0035538 carbohydrate response element binding
GO:0070888 E-box binding
GO:0034056 estrogen response element binding
GO:0140728 GC-box binding
GO:0070594 juvenile hormone response element binding
GO:0071820 N-box binding
GO:0044323 retinoic acid-responsive element binding
GO:0044377 RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending
GO:0010736 serum response element binding
GO:0032810 sterol response element binding
GO:0070644 vitamin D response element binding

Parents of RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978)

subject	relation	object
RNA polymerase II cis-regulatory region sequence-specific DNA binding	is_a	cis-regulatory region sequence-specific DNA binding (GO:0000987)
RNA polymerase II cis-regulatory region sequence-specific DNA binding	is_a	RNA polymerase II transcription regulatory region sequence-specific DNA binding (GO:0000977)
RNA polymerase II cis-regulatory region sequence-specific DNA binding	RO:0004009	enhancer (SO:0000165)

Children of RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978)

subject	relation	object
RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending (GO:0044377)	is_a	RNA polymerase II cis-regulatory region sequence-specific DNA binding
retinoic acid-responsive element binding (GO:0044323)	is_a	RNA polymerase II cis-regulatory region sequence-specific DNA binding
E-box binding (GO:0070888)	is_a	RNA polymerase II cis-regulatory region sequence-specific DNA binding
estrogen response element binding (GO:0034056)	is_a	RNA polymerase II cis-regulatory region sequence-specific DNA binding
sterol response element binding (GO:0032810)	is_a	RNA polymerase II cis-regulatory region sequence-specific DNA binding
cAMP response element binding (GO:0035497)	is_a	RNA polymerase II cis-regulatory region sequence-specific DNA binding
serum response element binding (GO:0010736)	is_a	RNA polymerase II cis-regulatory region sequence-specific DNA binding
carbohydrate response element binding (GO:0035538)	is_a	RNA polymerase II cis-regulatory region sequence-specific DNA binding
juvenile hormone response element binding (GO:0070594)	is_a	RNA polymerase II cis-regulatory region sequence-specific DNA binding
N-box binding (GO:0071820)	is_a	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GC-box binding (GO:0140728)	is_a	RNA polymerase II cis-regulatory region sequence-specific DNA binding
vitamin D response element binding (GO:0070644)	is_a	RNA polymerase II cis-regulatory region sequence-specific DNA binding

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