obsolete extrachromosomal circular DNA accumulation involved in replicative cell aging
Ontology
biological_process
Synonyms
extrachromosomal circular DNA accumulation during replicative cell ageing, extrachromosomal circular DNA accumulation during replicative cell aging
Alternate IDs
None
Definition
OBSOLETE. Increase in abundance of circular DNA molecules in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication.
Source:
GOC:jh
Comment
This term was obsoleted because it represents an assay, not a true biological process.
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