obsolete extrachromosomal rDNA circle accumulation involved in replicative cell aging
Ontology
biological_process
Synonyms
extrachromosomal rDNA circle accumulation during replicative cell ageing, extrachromosomal rDNA circle accumulation during replicative cell aging, extrachromosomal ribosomal DNA circle accumulation during replicative cell aging
Alternate IDs
None
Definition
OBSOLETE. Increase in abundance of circular DNA molecules containing ribosomal DNA repeats in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication.
Source:
GOC:jh,
PMID:12044934
Comment
This term was obsoleted because it represents an assay, not a true biological process.
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