Term Information

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Accession
GO:0001567
Name
cholesterol 25-hydroxylase activity
Ontology
molecular_function
Synonyms
cholesterol 25-monooxygenase activity, cholesterol,hydrogen-donor:oxygen oxidoreductase (25-hydroxylating) activity
Alternate IDs
None
Definition
Catalysis of the reaction: AH(2) + cholesterol + O2 = 25-hydroxycholesterol + A + H2O. Source: RHEA:21104, EC:1.14.99.38
Comment
None
History
See term history for GO:0001567 at QuickGO
Chem. react.
has participant hydrogen donor
has participant water
has participant 25-hydroxycholesterol
has participant cholesterol
has participant dioxygen
has participant hydrogen acceptor
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0001567 from QuickGO

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Parents of cholesterol 25-hydroxylase activity (GO:0001567)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cholesterol 25-hydroxylase activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705)
cholesterol 25-hydroxylase activity [RO:0000057 relation] RO:0000057  hydrogen donor (CHEBI:17499)
cholesterol 25-hydroxylase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
cholesterol 25-hydroxylase activity [RO:0000057 relation] RO:0000057  25-hydroxycholesterol (CHEBI:42977)
cholesterol 25-hydroxylase activity [RO:0000057 relation] RO:0000057  cholesterol (CHEBI:16113)
cholesterol 25-hydroxylase activity [RO:0000057 relation] RO:0000057  dioxygen (CHEBI:15379)
cholesterol 25-hydroxylase activity [RO:0000057 relation] RO:0000057  hydrogen acceptor (CHEBI:13193)
cholesterol 25-hydroxylase activity [is_a relation] is_a  steroid hydroxylase activity (GO:0008395)

This term has no children.

EC
1.14.99.38
KEGG_REACTION
R07218
MetaCyc
1.14.99.38-RXN
RHEA
21104