AmiGO 2: Term Details for "Gi/o-coupled serotonin receptor activity" (GO:0001586)

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Term Information

Accession: GO:0001586
Name: Gi/o-coupled serotonin receptor activity
Ontology: molecular_function
Synonyms: 5-HT1 receptor activity, serotonin receptor activity, coupled via Gi/o
Alternate IDs: None
Definition: Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels. Source: PMID:18571247, GOC:mah
Comment: None
History: See term history for GO:0001586 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to Gi/o-coupled serotonin receptor activity (excluding "regulates").; Link to all direct and indirect annotations to Gi/o-coupled serotonin receptor activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for Gi/o-coupled serotonin receptor activity (excluding "regulates").

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0003674 molecular_function
GO:0009987 cellular process
GO:0060089 molecular transducer activity
GO:0050789 regulation of biological process
GO:0050896 response to stimulus
GO:0007154 cell communication
GO:0051716 cellular response to stimulus
GO:0050794 regulation of cellular process
GO:0023052 signaling
GO:0038023 signaling receptor activity
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007165 signal transduction
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0008227 G protein-coupled amine receptor activity
GO:0098664 G protein-coupled serotonin receptor signaling pathway
GO:0004993 G protein-coupled serotonin receptor activity
GO:0001586 Gi/o-coupled serotonin receptor activity

Parents of Gi/o-coupled serotonin receptor activity (GO:0001586)

subject	relation	object
Gi/o-coupled serotonin receptor activity	is_a	G protein-coupled serotonin receptor activity (GO:0004993)

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