Term Information

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Accession
GO:0001772
Name
immunological synapse
Ontology
cellular_component
Synonyms
supramolecular activation cluster, c-SMAC
Alternate IDs
None
Definition
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction. Source: PMID:11244041, GOC:mgi_curators, PMID:11376300
Comment
None
History
See term history for GO:0001772 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0001772 from QuickGO

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Parents of immunological synapse (GO:0001772)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
immunological synapse [BFO:0000050 relation] BFO:0000050  plasma membrane (GO:0005886)
immunological synapse [is_a relation] is_a  cellular anatomical entity (GO:0110165)

This term has no children.