AmiGO 2: Term Details for "antibody-dependent cellular cytotoxicity" (GO:0001788)

Accession: GO:0001788
Name: antibody-dependent cellular cytotoxicity
Ontology: biological_process
Synonyms: ADCC, antibody dependent cell death, antibody dependent cell killing, antibody-dependent cell death, antibody-dependent cell killing, type VI hypersensitivity
Alternate IDs: None
Definition: Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells. Source: PMID:9581795, GOC:pr, ISBN:0781735149, PMID:11677095
Comment: None
History: See term history for GO:0001788 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to antibody-dependent cellular cytotoxicity (excluding "regulates").; Link to all direct and indirect annotations to antibody-dependent cellular cytotoxicity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for antibody-dependent cellular cytotoxicity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
antibody-dependent cellular cytotoxicity	is_a	type IIa hypersensitivity (GO:0001794)
antibody-dependent cellular cytotoxicity	is_a	leukocyte mediated cytotoxicity (GO:0001909)

subject	relation	object
positive regulation of antibody-dependent cellular cytotoxicity (GO:0001815)	RO:0002213	antibody-dependent cellular cytotoxicity
negative regulation of antibody-dependent cellular cytotoxicity (GO:0001814)	RO:0002212	antibody-dependent cellular cytotoxicity
regulation of antibody-dependent cellular cytotoxicity (GO:0001813)	RO:0002211	antibody-dependent cellular cytotoxicity

Wikipedia: Antibody-dependent_cell-mediated_cytotoxicity; Antibody-dependent_cellular_cytotoxicity