AmiGO 2: Term Details for "NK T cell differentiation" (GO:0001865)

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Term Information

Accession: GO:0001865
Name: NK T cell differentiation
Ontology: biological_process
Synonyms: NK T lymphocyte differentiation, NK T-cell differentiation, NK T-lymphocyte differentiation, NKT cell differentiation, NT cell differentiation, natural T cell differentiation, natural killer T cell differentiation, NK T cell development
Alternate IDs: None
Definition: The process in which a precursor cell type acquires the specialized features of a NK T cell. Source: PMID:10704459, ISBN:0781735149, GOC:add
Comment: Note that NK T cells are a distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
History: See term history for GO:0001865 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to NK T cell differentiation (excluding "regulates").; Link to all direct and indirect annotations to NK T cell differentiation (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for NK T cell differentiation (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0032502 developmental process
GO:0048856 anatomical structure development
GO:0030154 cell differentiation
GO:0048869 cellular developmental process
GO:0009987 cellular process
GO:0048468 cell development
GO:0032501 multicellular organismal process
GO:0001775 cell activation
GO:0030097 hemopoiesis
GO:0002376 immune system process
GO:0045321 leukocyte activation
GO:0002521 leukocyte differentiation
GO:0046649 lymphocyte activation
GO:1903131 mononuclear cell differentiation
GO:0030098 lymphocyte differentiation
GO:0042110 T cell activation
GO:0046631 alpha-beta T cell activation
GO:0030217 T cell differentiation
GO:0046632 alpha-beta T cell differentiation
GO:0001865 NK T cell differentiation
GO:0051137 negative regulation of NK T cell differentiation
GO:0002364 NK T cell lineage commitment
GO:0051138 positive regulation of NK T cell differentiation
GO:0051136 regulation of NK T cell differentiation

Parents of NK T cell differentiation (GO:0001865)

subject	relation	object
NK T cell differentiation	RO:0002162	Gnathostomata (NCBITaxon:7776)
NK T cell differentiation	is_a	alpha-beta T cell differentiation (GO:0046632)
NK T cell differentiation	RO:0002315	mature NK T cell (CL:0000814)

Children of NK T cell differentiation (GO:0001865)

subject	relation	object
NK T cell lineage commitment (GO:0002364)	BFO:0000050	NK T cell differentiation
negative regulation of NK T cell differentiation (GO:0051137)	RO:0002212	NK T cell differentiation
positive regulation of NK T cell differentiation (GO:0051138)	RO:0002213	NK T cell differentiation
regulation of NK T cell differentiation (GO:0051136)	RO:0002211	NK T cell differentiation

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