Term Information

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Accession
GO:0001905
Name
activation of membrane attack complex
Ontology
biological_process
Synonyms
MAC assembly, MAC formation, activation of MAC, membrane attack complex assembly, membrane attack complex formation, activation of TCC, activation of terminal complement complex, activation of the terminal complement cascade
Alternate IDs
None
Definition
The activation of the membrane attack complex components of the complement cascade which can result in death of a target cell through cytolysis. Source: ISBN:0781735149, GOC:add
Comment
None
History
See term history for GO:0001905 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0001905 from QuickGO

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Parents of activation of membrane attack complex (GO:0001905)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
activation of membrane attack complex [is_a relation] is_a  complement activation (GO:0006956)
Children of activation of membrane attack complex (GO:0001905)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of activation of membrane attack complex (GO:0001971) [RO:0002212 relation] RO:0002212  activation of membrane attack complex
regulation of activation of membrane attack complex (GO:0001969) [RO:0002211 relation] RO:0002211  activation of membrane attack complex
positive regulation of activation of membrane attack complex (GO:0001970) [RO:0002213 relation] RO:0002213  activation of membrane attack complex
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