AmiGO 2: Term Details for "B-1 B cell homeostasis" (GO:0001922)

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Term Information

Accession: GO:0001922
Name: B-1 B cell homeostasis
Ontology: biological_process
Synonyms: B-1 B lymphocyte homeostasis, B-1 B-cell homeostasis, B-1 B-lymphocyte homeostasis
Alternate IDs: None
Definition: The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. Source: ISBN:0781735149, GOC:add
Comment: Note that this term represents the return of B-1 B cell levels to stable numbers following an immune response, as well as the proliferation and elimination of B-1 B cells in a organism required to maintain stable numbers in the absence of an outside stimulus.
History: See term history for GO:0001922 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to B-1 B cell homeostasis (excluding "regulates").; Link to all direct and indirect annotations to B-1 B cell homeostasis (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for B-1 B cell homeostasis (excluding "regulates").

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GO:0008150 biological_process
GO:0042592 homeostatic process
GO:0032501 multicellular organismal process
GO:0048871 multicellular organismal-level homeostasis
GO:0048872 homeostasis of number of cells
GO:0002376 immune system process
GO:0001776 leukocyte homeostasis
GO:0002260 lymphocyte homeostasis
GO:0001782 B cell homeostasis
GO:0001922 B-1 B cell homeostasis

Parents of B-1 B cell homeostasis (GO:0001922)

subject	relation	object
B-1 B cell homeostasis	is_a	B cell homeostasis (GO:0001782)
B-1 B cell homeostasis	RO:0012003	B-1 B cell (CL:0000819)

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