AmiGO 2: Term Details for "B-1 B cell differentiation" (GO:0001923)

Accession: GO:0001923
Name: B-1 B cell differentiation
Ontology: biological_process
Synonyms: B-1 B lymphocyte differentiation, B-1 B-cell differentiation, B-1 B-lymphocyte differentiation, B-1 B cell development
Alternate IDs: None
Definition: The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. Source: ISBN:0781735149, GOC:add
Comment: None
History: See term history for GO:0001923 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to B-1 B cell differentiation (excluding "regulates").; Link to all direct and indirect annotations to B-1 B cell differentiation (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for B-1 B cell differentiation (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
B-1 B cell differentiation	is_a	mature B cell differentiation (GO:0002335)
B-1 B cell differentiation	RO:0002315	B-1 B cell (CL:0000819)

subject	relation	object
regulation of B-1 B cell differentiation (GO:0001924)	RO:0002211	B-1 B cell differentiation
positive regulation of B-1 B cell differentiation (GO:0001926)	RO:0002213	B-1 B cell differentiation
B-1b B cell differentiation (GO:0002338)	is_a	B-1 B cell differentiation
B-1a B cell differentiation (GO:0002337)	is_a	B-1 B cell differentiation
negative regulation of B-1 B cell differentiation (GO:0001925)	RO:0002212	B-1 B cell differentiation
B-1 B cell lineage commitment (GO:0002336)	BFO:0000050	B-1 B cell differentiation

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