AmiGO 2: Term Details for "cap-dependent translational initiation" (GO:0002191)

Accession: GO:0002191
Name: cap-dependent translational initiation
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation. Source: PMID:19604130, PMID:17284590
Comment: None
History: See term history for GO:0002191 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to cap-dependent translational initiation (excluding "regulates").; Link to all direct and indirect annotations to cap-dependent translational initiation (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for cap-dependent translational initiation (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
cap-dependent translational initiation	is_a	cytoplasmic translational initiation (GO:0002183)

subject	relation	object
histone mRNA stem-loop binding complex (GO:0062073)	RO:0002216	cap-dependent translational initiation
negative regulation of cap-dependent translational initiation (GO:1903675)	RO:0002212	cap-dependent translational initiation
regulation of cap-dependent translational initiation (GO:1903674)	RO:0002211	cap-dependent translational initiation
positive regulation of cap-dependent translational initiation (GO:1903676)	RO:0002213	cap-dependent translational initiation

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