AmiGO 2: Term Details for "tissue kallikrein-kinin cascade" (GO:0002255)

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Term Information

Accession: GO:0002255
Name: tissue kallikrein-kinin cascade
Ontology: biological_process
Synonyms: glandular kallikrein-kinin cascade
Alternate IDs: None
Definition: A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability. Source: PMID:11842287, PMID:14501145, GOC:add
Comment: None
History: See term history for GO:0002255 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to tissue kallikrein-kinin cascade (excluding "regulates").; Link to all direct and indirect annotations to tissue kallikrein-kinin cascade (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for tissue kallikrein-kinin cascade (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0071704 organic substance metabolic process
GO:0044249 cellular biosynthetic process
GO:0043170 macromolecule metabolic process
GO:1901576 organic substance biosynthetic process
GO:0050896 response to stimulus
GO:0009059 macromolecule biosynthetic process
GO:1901564 organonitrogen compound metabolic process
GO:0044238 primary metabolic process
GO:0006950 response to stress
GO:0006952 defense response
GO:0010467 gene expression
GO:0019538 protein metabolic process
GO:0006954 inflammatory response
GO:0051604 protein maturation
GO:0002526 acute inflammatory response
GO:0072376 protein activation cascade
GO:0002254 kinin cascade
GO:0002255 tissue kallikrein-kinin cascade
GO:0002546 negative regulation of tissue kallikrein-kinin cascade
GO:0002547 positive regulation of tissue kallikrein-kinin cascade
GO:0002382 regulation of tissue kallikrein-kinin cascade

Parents of tissue kallikrein-kinin cascade (GO:0002255)

subject	relation	object
tissue kallikrein-kinin cascade	is_a	kinin cascade (GO:0002254)

Children of tissue kallikrein-kinin cascade (GO:0002255)

subject	relation	object
negative regulation of tissue kallikrein-kinin cascade (GO:0002546)	RO:0002212	tissue kallikrein-kinin cascade
regulation of tissue kallikrein-kinin cascade (GO:0002382)	RO:0002211	tissue kallikrein-kinin cascade
positive regulation of tissue kallikrein-kinin cascade (GO:0002547)	RO:0002213	tissue kallikrein-kinin cascade

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