AmiGO 2: Term Details for "pre-B cell differentiation" (GO:0002329)

Accession: GO:0002329
Name: pre-B cell differentiation
Ontology: biological_process
Synonyms: pre-B lymphocyte differentiation, pre-B cell development
Alternate IDs: None
Definition: The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments. Source: ISBN:0781735149, GOC:jal
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
History: See term history for GO:0002329 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to pre-B cell differentiation (excluding "regulates").; Link to all direct and indirect annotations to pre-B cell differentiation (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for pre-B cell differentiation (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
pre-B cell differentiation	is_a	immature B cell differentiation (GO:0002327)
pre-B cell differentiation	RO:0002315	precursor B cell (CL:0000817)

subject	relation	object
pre-B cell allelic exclusion (GO:0002331)	BFO:0000050	pre-B cell differentiation
pre-B cell receptor expression (GO:0002330)	BFO:0000050	pre-B cell differentiation

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