AmiGO 2: Term Details for "germinal center formation" (GO:0002467)

Accession: GO:0002467
Name: germinal center formation
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation. Source: GO_REF:0000022, ISBN:081533642X, GOC:jal
Comment: None
History: See term history for GO:0002467 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to germinal center formation (excluding "regulates").; Link to all direct and indirect annotations to germinal center formation (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for germinal center formation (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
germinal center formation	RO:0002162	Mammalia (NCBITaxon:40674)
germinal center formation	is_a	anatomical structure formation involved in morphogenesis (GO:0048646)
germinal center formation	RO:0002297	secondary nodular lymphoid tissue (UBERON:0001745)
germinal center formation	is_a	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002460)

subject	relation	object
negative regulation of germinal center formation (GO:0002635)	RO:0002212	germinal center formation
regulation of germinal center formation (GO:0002634)	RO:0002211	germinal center formation
positive regulation of germinal center formation (GO:0002636)	RO:0002213	germinal center formation

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