AmiGO 2: Term Details for "antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent" (GO:0002479)

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Term Information

Accession: GO:0002479
Name: antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
Ontology: biological_process
Synonyms: TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent exogenous peptide antigen processing and presentation via MHC class I, exogenous peptide antigen processing and presentation via MHC class I, TAP-dependent, cross presentation, cross-presentation
Alternate IDs: None
Definition: The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules. Source: PMID:15224093, GOC:add, PMID:15771591, PMID:16181335
Comment: None
History: See term history for GO:0002479 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (excluding "regulates").; Link to all direct and indirect annotations to antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (excluding "regulates").

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GO:0008150 biological_process
GO:0002376 immune system process
GO:0019882 antigen processing and presentation
GO:0019884 antigen processing and presentation of exogenous antigen
GO:0048002 antigen processing and presentation of peptide antigen
GO:0002478 antigen processing and presentation of exogenous peptide antigen
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

Parents of antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:0002479)

subject	relation	object
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	is_a	antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)

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