Term Information

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Accession
GO:0002484
Name
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway
Ontology
biological_process
Synonyms
endogenous peptide antigen processing and presentation via MHC class I via ER pathway
Alternate IDs
None
Definition
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules. Source: ISBN:0781735149, PMID:14647477, GOC:add, PMID:15771591
Comment
None
History
See term history for GO:0002484 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway (GO:0002484)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway [is_a relation] is_a  antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)
Children of antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway (GO:0002484)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent (GO:0002485) [is_a relation] is_a  antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent (GO:0002486) [is_a relation] is_a  antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway
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