AmiGO 2: Term Details for "Factor XII activation" (GO:0002542)

Term Information

Accession: GO:0002542
Name: Factor XII activation
Ontology: biological_process
Synonyms: Hageman factor activation
Alternate IDs: None
Definition: Any process that activates Factor XII (Hageman factor). Factor XII is a protein synthesized by the liver that circulates in an inactive form until it encounters collagen or basement membrane or activated platelets (as occurs at the site of endothelial injury). Factor XII then undergoes a conformational change (becoming factor XIIa), exposing an active serine center that can subsequently cleave protein substrates and activate a variety of mediator systems. Factor XII is a participant in the clotting cascade as well as the kinin cascade. Source: ISBN:0721601871, GOC:jal
Comment: None
History: See term history for GO:0002542 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to Factor XII activation (excluding "regulates").; Link to all direct and indirect annotations to Factor XII activation (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for Factor XII activation (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0008152 metabolic process
GO:0048518 positive regulation of biological process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
GO:0044249 cellular biosynthetic process
GO:0071704 organic substance metabolic process
GO:0048522 positive regulation of cellular process
GO:0009893 positive regulation of metabolic process
GO:0009889 regulation of biosynthetic process
GO:0031323 regulation of cellular metabolic process
GO:0065007 biological regulation
GO:0009059 macromolecule biosynthetic process
GO:0043170 macromolecule metabolic process
GO:0006807 nitrogen compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0009891 positive regulation of biosynthetic process
GO:0031325 positive regulation of cellular metabolic process
GO:0044238 primary metabolic process
GO:0031326 regulation of cellular biosynthetic process
GO:0060255 regulation of macromolecule metabolic process
GO:0050896 response to stimulus
GO:0010467 gene expression
GO:1901564 organonitrogen compound metabolic process
GO:0031328 positive regulation of cellular biosynthetic process
GO:0010604 positive regulation of macromolecule metabolic process
GO:0019538 protein metabolic process
GO:0010556 regulation of macromolecule biosynthetic process
GO:0051171 regulation of nitrogen compound metabolic process
GO:0080090 regulation of primary metabolic process
GO:0048583 regulation of response to stimulus
GO:0006950 response to stress
GO:0006952 defense response
GO:0010557 positive regulation of macromolecule biosynthetic process
GO:0051173 positive regulation of nitrogen compound metabolic process
GO:0051604 protein maturation
GO:0006508 proteolysis
GO:0010468 regulation of gene expression
GO:0051246 regulation of protein metabolic process
GO:0080134 regulation of response to stress
GO:0009605 response to external stimulus
GO:0002526 acute inflammatory response
GO:0006954 inflammatory response
GO:0010628 positive regulation of gene expression
GO:0051247 positive regulation of protein metabolic process
GO:0072376 protein activation cascade
GO:0016485 protein processing
GO:0031347 regulation of defense response
GO:1903317 regulation of protein maturation
GO:0030162 regulation of proteolysis
GO:0032101 regulation of response to external stimulus
GO:0002254 kinin cascade
GO:1903319 positive regulation of protein maturation
GO:0045862 positive regulation of proteolysis
GO:0050727 regulation of inflammatory response
GO:0070613 regulation of protein processing
GO:0002541 activation of plasma proteins involved in acute inflammatory response
GO:0002353 plasma kallikrein-kinin cascade
GO:0010954 positive regulation of protein processing
GO:0002673 regulation of acute inflammatory response
GO:0002542 Factor XII activation

Parents of Factor XII activation (GO:0002542)

subject	relation	object
Factor XII activation	is_a	regulation of acute inflammatory response (GO:0002673)
Factor XII activation	BFO:0000050	plasma kallikrein-kinin cascade (GO:0002353)
Factor XII activation	RO:0002213	activation of plasma proteins involved in acute inflammatory response (GO:0002541)
Factor XII activation	is_a	positive regulation of protein processing (GO:0010954)
Factor XII activation	RO:0002162	Vertebrata (NCBITaxon:7742)

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