AmiGO 2: Term Details for "cytoplasmic pattern recognition receptor signaling pathway" (GO:0002753)

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Term Information

Accession: GO:0002753
Name: cytoplasmic pattern recognition receptor signaling pathway
Ontology: biological_process
Synonyms: cytoplasmic PRR signaling pathway, cytoplasmic pathogen receptor signaling pathway, cytoplasmic pattern recognition receptor signalling pathway, cytosolic PAMP receptor signaling pathway, cytosolic pattern recognition receptor signaling pathway, cytoplasmic caspase-recruiting domain (CARD) helicase signaling pathway
Alternate IDs: GO:0039528
Definition: The series of molecular signals initiated by the binding of a ligand from another organism to a cytoplasmic pattern recognition receptor (PRR). PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species. Source: PMID:21187438, PMID:15199967, PMID:18272355, ISBN:0781735149, GOC:ar, GOC:add, PMID:19531363, PMID:17328678
Comment: This term should be used for annotation when it is not known which cytoplasmic pattern recognition receptor (PRR) has been activated. If the PRR is known, consider instead the child terms. The RIG-like family is composed of at least RIG-I (retinoic acid inducible gene I; also known as DDX58), melanoma differentiation-associated gene 5 (MDA5; also known as helicard or IFIH1) and LGP2.
History: See term history for GO:0002753 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to cytoplasmic pattern recognition receptor signaling pathway (excluding "regulates").; Link to all direct and indirect annotations to cytoplasmic pattern recognition receptor signaling pathway (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for cytoplasmic pattern recognition receptor signaling pathway (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009607 response to biotic stimulus
GO:0009605 response to external stimulus
GO:0044419 biological process involved in interspecies interaction between organisms
GO:0043207 response to external biotic stimulus
GO:0006952 defense response
GO:0050789 regulation of biological process
GO:0048583 regulation of response to stimulus
GO:0051707 response to other organism
GO:0050896 response to stimulus
GO:0006950 response to stress
GO:0098542 defense response to other organism
GO:0002376 immune system process
GO:0048518 positive regulation of biological process
GO:0002682 regulation of immune system process
GO:0080134 regulation of response to stress
GO:0140546 defense response to symbiont
GO:0006955 immune response
GO:0045087 innate immune response
GO:0002684 positive regulation of immune system process
GO:0048584 positive regulation of response to stimulus
GO:0031347 regulation of defense response
GO:0050776 regulation of immune response
GO:0002831 regulation of response to biotic stimulus
GO:0032101 regulation of response to external stimulus
GO:0065007 biological regulation
GO:0031349 positive regulation of defense response
GO:0050778 positive regulation of immune response
GO:0002833 positive regulation of response to biotic stimulus
GO:0032103 positive regulation of response to external stimulus
GO:0045088 regulation of innate immune response
GO:0007165 signal transduction
GO:0002253 activation of immune response
GO:0009987 cellular process
GO:0002764 immune response-regulating signaling pathway
GO:0045089 positive regulation of innate immune response
GO:0002218 activation of innate immune response
GO:0007154 cell communication
GO:0051716 cellular response to stimulus
GO:0002757 immune response-activating signaling pathway
GO:0050794 regulation of cellular process
GO:0023052 signaling
GO:0002758 innate immune response-activating signaling pathway
GO:0030522 intracellular receptor signaling pathway
GO:0002221 pattern recognition receptor signaling pathway
GO:0002753 cytoplasmic pattern recognition receptor signaling pathway
GO:0140896 cGAS/STING signaling pathway
GO:0140894 endolysosomal toll-like receptor signaling pathway
GO:0002754 endosomal pattern recognition receptor signaling pathway
GO:0141084 inflammasome-mediated signaling pathway
GO:0039530 MDA-5 signaling pathway
GO:0039532 negative regulation of cytoplasmic pattern recognition receptor signaling pathway
GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0039531 regulation of cytoplasmic pattern recognition receptor signaling pathway
GO:0039529 RIG-I signaling pathway

Parents of cytoplasmic pattern recognition receptor signaling pathway (GO:0002753)

subject	relation	object
cytoplasmic pattern recognition receptor signaling pathway	is_a	pattern recognition receptor signaling pathway (GO:0002221)
cytoplasmic pattern recognition receptor signaling pathway	BFO:0000051	positive regulation of cytokine production (GO:0001819)
cytoplasmic pattern recognition receptor signaling pathway	is_a	intracellular receptor signaling pathway (GO:0030522)

Children of cytoplasmic pattern recognition receptor signaling pathway (GO:0002753)

subject	relation	object
regulation of cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)	RO:0002211	cytoplasmic pattern recognition receptor signaling pathway
endolysosomal toll-like receptor signaling pathway (GO:0140894)	is_a	cytoplasmic pattern recognition receptor signaling pathway
RIG-I signaling pathway (GO:0039529)	is_a	cytoplasmic pattern recognition receptor signaling pathway
MDA-5 signaling pathway (GO:0039530)	is_a	cytoplasmic pattern recognition receptor signaling pathway
endosomal pattern recognition receptor signaling pathway (GO:0002754)	is_a	cytoplasmic pattern recognition receptor signaling pathway
inflammasome-mediated signaling pathway (GO:0141084)	is_a	cytoplasmic pattern recognition receptor signaling pathway
cGAS/STING signaling pathway (GO:0140896)	is_a	cytoplasmic pattern recognition receptor signaling pathway
negative regulation of cytoplasmic pattern recognition receptor signaling pathway (GO:0039532)	RO:0002212	cytoplasmic pattern recognition receptor signaling pathway
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (GO:0035872)	is_a	cytoplasmic pattern recognition receptor signaling pathway

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