AmiGO 2: Term Details for "tRNA 4-thiouridine biosynthesis" (GO:0002937)

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Term Information

Accession: GO:0002937
Name: tRNA 4-thiouridine biosynthesis
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs. Source: ISBN:155581073X
Comment: In E. coli, two genes are involved, nuvA (aka Thi) and NuvC (aka iscS) . NuvA converts the trNA into an unidentified intermediate in an ATP dependent manner. NucC catalyzes the second step, transferring the sulfur from cysteine to an unidentified intermediate. NuvC also participates in thiamine synthesis.
History: See term history for GO:0002937 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to tRNA 4-thiouridine biosynthesis (excluding "regulates").; Link to all direct and indirect annotations to tRNA 4-thiouridine biosynthesis (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for tRNA 4-thiouridine biosynthesis (excluding "regulates").

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0071704 organic substance metabolic process
GO:0044249 cellular biosynthetic process
GO:0043170 macromolecule metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0044238 primary metabolic process
GO:0009059 macromolecule biosynthetic process
GO:0006139 nucleobase-containing compound metabolic process
GO:0016070 RNA metabolic process
GO:0010467 gene expression
GO:0034660 ncRNA metabolic process
GO:0090304 nucleic acid metabolic process
GO:0043412 macromolecule modification
GO:0141188 nucleic acid catabolic process
GO:0006396 RNA processing
GO:0006399 tRNA metabolic process
GO:0009451 RNA modification
GO:0008033 tRNA processing
GO:0006400 tRNA modification
GO:0034227 tRNA thio-modification
GO:0002937 tRNA 4-thiouridine biosynthesis

Parents of tRNA 4-thiouridine biosynthesis (GO:0002937)

subject	relation	object
tRNA 4-thiouridine biosynthesis	is_a	tRNA thio-modification (GO:0034227)

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