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alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity

Term Information

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Accession
GO:0003828
Name
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
Ontology
molecular_function
Synonyms
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase activity, alpha-2,8-sialyltransferase activity, cytidine monophosphoacetylneuraminate-ganglioside GM3, ganglioside GD3 synthase activity, ganglioside GD3 synthetase sialyltransferase activity
Alternate IDs
None
Definition
Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R. Source: EC:2.4.3.8
Comment
None
History
See term history for GO:0003828 at QuickGO
Chem. react.
has participant alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactoside(2-)
has participant hydron
has participant CMP-N-acetyl-beta-neuraminate(2-)
has participant cytidine 5'-monophosphate(2-)
has participant alpha-N-acetylneuraminyl-(2->3)-beta-D-galactoside(1-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0003828 from QuickGO

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Parents of alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity (GO:0003828)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity [RO:0000057 relation] RO:0000057  alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactoside(2-) (CHEBI:140309)
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity [is_a relation] is_a  sialyltransferase activity (GO:0008373)
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity [RO:0000057 relation] RO:0000057  CMP-N-acetyl-beta-neuraminate(2-) (CHEBI:57812)
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity [RO:0000057 relation] RO:0000057  cytidine 5'-monophosphate(2-) (CHEBI:60377)
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity [RO:0000057 relation] RO:0000057  alpha-N-acetylneuraminyl-(2->3)-beta-D-galactoside(1-) (CHEBI:140308)

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