AmiGO 2: Term Details for "3-isopropylmalate dehydrogenase activity" (GO:0003862)

Accession: GO:0003862
Name: 3-isopropylmalate dehydrogenase activity
Ontology: molecular_function
Synonyms: (2R,3S)-3-isopropylmalate:NAD+ oxidoreductase activity, 3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase activity, IMDH activity, IPMDH, beta-IPM dehydrogenase activity, beta-isopropylmalate dehydrogenase activity, beta-isopropylmalic enzyme, threo-Ds-3-isopropylmalate dehydrogenase activity
Alternate IDs: None
Definition: Catalysis of the reaction: 3-carboxy-2-hydroxy-4-methylpentanoate + NAD+ = 3-carboxy-4-methyl-2-oxopentanoate + NADH + H+. Source: EC:1.1.1.85, RHEA:32271
Comment: None
History: See term history for GO:0003862 at QuickGO
Chem. react.: has participant NAD(1-); has participant NADH(2-); has participant 4-methyl-2-oxopentanoate; has participant (2R,3S)-3-isopropylmalate(2-); has participant carbon dioxide
Subset: None
Related: Link to all genes and gene products annotated to 3-isopropylmalate dehydrogenase activity (excluding "regulates").; Link to all direct and indirect annotations to 3-isopropylmalate dehydrogenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for 3-isopropylmalate dehydrogenase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
3-isopropylmalate dehydrogenase activity	RO:0000057	NAD(1-) (CHEBI:57540)
3-isopropylmalate dehydrogenase activity	RO:0000057	NADH(2-) (CHEBI:57945)
3-isopropylmalate dehydrogenase activity	RO:0000057	4-methyl-2-oxopentanoate (CHEBI:17865)
3-isopropylmalate dehydrogenase activity	RO:0000057	(2R,3S)-3-isopropylmalate(2-) (CHEBI:35121)
3-isopropylmalate dehydrogenase activity	RO:0000057	carbon dioxide (CHEBI:16526)
3-isopropylmalate dehydrogenase activity	is_a	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)

This term has no children.