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3-methyl-2-oxobutanoate hydroxymethyltransferase activity

Term Information

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Accession
GO:0003864
Name
3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Ontology
molecular_function
Synonyms
5,10-methylene tetrahydrofolate:alpha-ketoisovalerate hydroxymethyltransferase activity, 5,10-methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase activity, alpha-ketoisovalerate hydroxymethyltransferase activity, dehydropantoate hydroxymethyltransferase activity, ketopantoate hydroxymethyltransferase activity, oxopantoate hydroxymethyltransferase activity
Alternate IDs
None
Definition
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate. Source: EC:2.1.2.11
Comment
None
History
See term history for GO:0003864 at QuickGO
Chem. react.
has participant (6R)-5,10-methylenetetrahydrofolate(2-)
has participant 2-dehydropantoate
has participant water
has participant 3-methyl-2-oxobutanoate
has participant (6S)-5,6,7,8-tetrahydrofolate(2-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of 3-methyl-2-oxobutanoate hydroxymethyltransferase activity (GO:0003864)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
3-methyl-2-oxobutanoate hydroxymethyltransferase activity [RO:0000057 relation] RO:0000057  (6R)-5,10-methylenetetrahydrofolate(2-) (CHEBI:15636)
3-methyl-2-oxobutanoate hydroxymethyltransferase activity [is_a relation] is_a  hydroxymethyl-, formyl- and related transferase activity (GO:0016742)
3-methyl-2-oxobutanoate hydroxymethyltransferase activity [RO:0000057 relation] RO:0000057  2-dehydropantoate (CHEBI:11561)
3-methyl-2-oxobutanoate hydroxymethyltransferase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
3-methyl-2-oxobutanoate hydroxymethyltransferase activity [RO:0000057 relation] RO:0000057  3-methyl-2-oxobutanoate (CHEBI:11851)
3-methyl-2-oxobutanoate hydroxymethyltransferase activity [RO:0000057 relation] RO:0000057  (6S)-5,6,7,8-tetrahydrofolate(2-) (CHEBI:57453)

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