AmiGO 2: Term Details for "3-oxo-5-alpha-steroid 4-dehydrogenase activity" (GO:0003865)

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Term Information

Accession: GO:0003865
Name: 3-oxo-5-alpha-steroid 4-dehydrogenase activity
Ontology: molecular_function
Synonyms: 3-keto-delta4-steroid-5alpha-reductase activity, 3-oxo-5alpha-steroid 4-dehydrogenase activity, 3-oxo-5alpha-steroid delta4-dehydrogenase activity, 3-oxo-5alpha-steroid:(acceptor) delta4-oxidoreductase activity, 3-oxo-5alpha-steroid:acceptor delta4-oxidoreductase activity, 4-ene-3-ketosteroid-5alpha-oxidoreductase activity, delta4-3-keto steroid 5alpha-reductase activity, delta4-3-ketosteroid5alpha-oxidoreductase activity, delta4-3-oxo steroid reductase activity, delta4-5alpha-dehydrogenase activity, steroid delta4-5alpha-reductase activity, 3-oxosteroid delta4-dehydrogenase, 5alpha-reductase, delta4-3-oxosteroid-5alpha-reductase, steroid 5 alpha reductase, steroid 5-alpha-reductase activity, steroid 5alpha-reductase, testosterone 5alpha-reductase
Alternate IDs: None
Definition: Catalysis of the reaction: a 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-delta(4)-steroid + reduced acceptor. Source: EC:1.3.99.5
Comment: None
History: See term history for GO:0003865 at QuickGO
Chem. react.: has participant 3-oxo-Delta(4) steroid; has participant hydrogen donor; has participant hydrogen acceptor; has participant 3-oxo-5alpha-steroid
Subset: None
Related: Link to all genes and gene products annotated to 3-oxo-5-alpha-steroid 4-dehydrogenase activity (excluding "regulates").; Link to all direct and indirect annotations to 3-oxo-5-alpha-steroid 4-dehydrogenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for 3-oxo-5-alpha-steroid 4-dehydrogenase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0016229 steroid dehydrogenase activity
GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors
GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity
GO:0047751 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) activity

Parents of 3-oxo-5-alpha-steroid 4-dehydrogenase activity (GO:0003865)

subject	relation	object
3-oxo-5-alpha-steroid 4-dehydrogenase activity	is_a	steroid dehydrogenase activity, acting on the CH-CH group of donors (GO:0033765)
3-oxo-5-alpha-steroid 4-dehydrogenase activity	RO:0000057	3-oxo-Delta(4) steroid (CHEBI:47909)
3-oxo-5-alpha-steroid 4-dehydrogenase activity	RO:0000057	hydrogen donor (CHEBI:17499)
3-oxo-5-alpha-steroid 4-dehydrogenase activity	RO:0000057	hydrogen acceptor (CHEBI:13193)
3-oxo-5-alpha-steroid 4-dehydrogenase activity	RO:0000057	3-oxo-5alpha-steroid (CHEBI:13601)

Children of 3-oxo-5-alpha-steroid 4-dehydrogenase activity (GO:0003865)

subject	relation	object
3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) activity (GO:0047751)	is_a	3-oxo-5-alpha-steroid 4-dehydrogenase activity

EC: 1.3.99.5
MetaCyc: 1.3.99.5-RXN
Reactome: R-HSA-9705714; R-HSA-9705713; R-HSA-469659
RHEA: 13805