AmiGO 2: Term Details for "5-aminolevulinate synthase activity" (GO:0003870)

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Term Information

Accession: GO:0003870
Name: 5-aminolevulinate synthase activity
Ontology: molecular_function
Synonyms: 5-aminolevulinate synthetase activity, 5-aminolevulinic acid synthase activity, 5-aminolevulinic acid synthetase activity, ALA synthase activity, ALA synthetase activity, ALAS activity, alpha-aminolevulinic acid synthase activity, aminolevulinate synthase activity, aminolevulinate synthetase activity, aminolevulinic acid synthase activity, aminolevulinic acid synthetase activity, aminolevulinic synthetase activity, delta-ALA synthetase activity, delta-aminolevulinate synthase activity, delta-aminolevulinate synthetase activity, delta-aminolevulinic acid synthase activity, delta-aminolevulinic acid synthetase activity, delta-aminolevulinic synthetase activity, succinyl-CoA:glycine C-succinyltransferase (decarboxylating)
Alternate IDs: None
Definition: Catalysis of the reaction: glycine + H+ + succinyl-CoA = 5-aminolevulinate + CO2 + CoA. Source: RHEA:12921, EC:2.3.1.37
Comment: None
History: See term history for GO:0003870 at QuickGO
Chem. react.: has participant carbon dioxide; has participant coenzyme A(4-); has participant glycine zwitterion; has participant hydron; has participant succinyl-CoA(5-); has participant 5-ammoniolevulinate
Subset: None
Related: Link to all genes and gene products annotated to 5-aminolevulinate synthase activity (excluding "regulates").; Link to all direct and indirect annotations to 5-aminolevulinate synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for 5-aminolevulinate synthase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0016410 N-acyltransferase activity
GO:0016748 succinyltransferase activity
GO:0016749 N-succinyltransferase activity
GO:0003870 5-aminolevulinate synthase activity

Parents of 5-aminolevulinate synthase activity (GO:0003870)

subject	relation	object
5-aminolevulinate synthase activity	RO:0000057	carbon dioxide (CHEBI:16526)
5-aminolevulinate synthase activity	RO:0000057	coenzyme A(4-) (CHEBI:57287)
5-aminolevulinate synthase activity	is_a	N-succinyltransferase activity (GO:0016749)
5-aminolevulinate synthase activity	RO:0000057	glycine zwitterion (CHEBI:57305)
5-aminolevulinate synthase activity	RO:0000057	hydron (CHEBI:15378)
5-aminolevulinate synthase activity	RO:0000057	succinyl-CoA(5-) (CHEBI:57292)
5-aminolevulinate synthase activity	RO:0000057	5-ammoniolevulinate (CHEBI:356416)

This term has no children.

EC: 2.3.1.37
KEGG_REACTION: R00830
MetaCyc: 5-AMINOLEVULINIC-ACID-SYNTHASE-RXN
Reactome: R-HSA-189442
RHEA: 12921