Term Information

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Accession
GO:0003874
Name
6-pyruvoyltetrahydropterin synthase activity
Ontology
molecular_function
Synonyms
2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate lyase activity, 2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming), 6-pyruvoyl tetrahydrobiopterin synthase activity, PTPS activity
Alternate IDs
None
Definition
Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H+ + triphosphate. Source: RHEA:22048, EC:4.2.3.12
Comment
None
History
See term history for GO:0003874 at QuickGO
Chem. react.
has participant hydron
has participant (R)-dyspropterin
has participant 7,8-dihydroneopterin 3'-triphosphate(4-)
has participant triphosphate(5-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of 6-pyruvoyltetrahydropterin synthase activity (GO:0003874)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
6-pyruvoyltetrahydropterin synthase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
6-pyruvoyltetrahydropterin synthase activity [RO:0000057 relation] RO:0000057  (R)-dyspropterin (CHEBI:136564)
6-pyruvoyltetrahydropterin synthase activity [is_a relation] is_a  carbon-oxygen lyase activity, acting on phosphates (GO:0016838)
6-pyruvoyltetrahydropterin synthase activity [RO:0000057 relation] RO:0000057  7,8-dihydroneopterin 3'-triphosphate(4-) (CHEBI:58462)
6-pyruvoyltetrahydropterin synthase activity [RO:0000057 relation] RO:0000057  triphosphate(5-) (CHEBI:18036)

This term has no children.

EC
4.2.3.12
KEGG_REACTION
R04286
MetaCyc
4.2.3.12-RXN
Reactome
R-HSA-1474184
RHEA
22048