AmiGO 2: Term Details for "alkylbase DNA N-glycosylase activity" (GO:0003905)

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Term Information

Accession: GO:0003905
Name: alkylbase DNA N-glycosylase activity
Ontology: molecular_function
Synonyms: DNA-3-methyladenine glycosidase II activity, alkylbase DNA glycosidase activity, 3-methyladenine DNA glycosylase II, AlkA, DNA glycosidase II activity, DNA-3-methyladenine glycosylase II, deoxyribonucleate 3-methyladenine glycosidase II, alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)
Alternate IDs: GO:0004036
Definition: Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site. Source: PMID:9224623, PMID:10872450, EC:3.2.2.21, GOC:elh
Comment: None
History: See term history for GO:0003905 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to alkylbase DNA N-glycosylase activity (excluding "regulates").; Link to all direct and indirect annotations to alkylbase DNA N-glycosylase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for alkylbase DNA N-glycosylase activity (excluding "regulates").

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GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:0016787 hydrolase activity
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0140097 catalytic activity, acting on DNA
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0019104 DNA N-glycosylase activity
GO:0003905 alkylbase DNA N-glycosylase activity
GO:0052820 DNA-1,N6-ethenoadenine N-glycosylase activity
GO:0043733 DNA-3-methylbase glycosylase activity
GO:1990053 DNA-5-methylcytosine glycosylase activity
GO:0052821 DNA-7-methyladenine glycosylase activity
GO:0043916 DNA-7-methylguanine glycosylase activity

Parents of alkylbase DNA N-glycosylase activity (GO:0003905)

subject	relation	object
alkylbase DNA N-glycosylase activity	is_a	DNA N-glycosylase activity (GO:0019104)

Children of alkylbase DNA N-glycosylase activity (GO:0003905)

subject	relation	object
DNA-7-methyladenine glycosylase activity (GO:0052821)	is_a	alkylbase DNA N-glycosylase activity
DNA-5-methylcytosine glycosylase activity (GO:1990053)	is_a	alkylbase DNA N-glycosylase activity
DNA-7-methylguanine glycosylase activity (GO:0043916)	is_a	alkylbase DNA N-glycosylase activity
DNA-1,N6-ethenoadenine N-glycosylase activity (GO:0052820)	is_a	alkylbase DNA N-glycosylase activity
DNA-3-methylbase glycosylase activity (GO:0043733)	is_a	alkylbase DNA N-glycosylase activity

EC: 3.2.2.21
MetaCyc: 3.2.2.21-RXN