AmiGO 2: Term Details for "DNA ligase activity" (GO:0003909)

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Term Information

Accession: GO:0003909
Name: DNA ligase activity
Ontology: molecular_function
Synonyms: None
Alternate IDs: None
Definition: Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+. Source: ISBN:0716720094
Comment: None
History: See term history for GO:0003909 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to DNA ligase activity (excluding "regulates").; Link to all direct and indirect annotations to DNA ligase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for DNA ligase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0016874 ligase activity
GO:0140097 catalytic activity, acting on DNA
GO:0016886 ligase activity, forming phosphoric ester bonds
GO:0003909 DNA ligase activity
GO:0003910 DNA ligase (ATP) activity
GO:0003911 DNA ligase (NAD+) activity
GO:1904876 negative regulation of DNA ligase activity
GO:1904877 positive regulation of DNA ligase activity
GO:1904875 regulation of DNA ligase activity

Parents of DNA ligase activity (GO:0003909)

subject	relation	object
DNA ligase activity	is_a	ligase activity, forming phosphoric ester bonds (GO:0016886)
DNA ligase activity	is_a	catalytic activity, acting on DNA (GO:0140097)

Children of DNA ligase activity (GO:0003909)

subject	relation	object
positive regulation of DNA ligase activity (GO:1904877)	RO:0002213	DNA ligase activity
regulation of DNA ligase activity (GO:1904875)	RO:0002211	DNA ligase activity
negative regulation of DNA ligase activity (GO:1904876)	RO:0002212	DNA ligase activity
DNA ligase (NAD+) activity (GO:0003911)	is_a	DNA ligase activity
DNA ligase (ATP) activity (GO:0003910)	is_a	DNA ligase activity

Reactome: R-HSA-174456; R-HSA-5690997; R-HSA-5693604; R-HSA-175258; R-HSA-5651805; R-HSA-5649734; R-HSA-5687675; R-HSA-5651789; R-HSA-73931; R-HSA-69173; R-HSA-5358592; R-HSA-6782227