AmiGO 2: Term Details for "DNA topoisomerase activity" (GO:0003916)

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Term Information

Accession: GO:0003916
Name: DNA topoisomerase activity
Ontology: molecular_function
Synonyms: None
Alternate IDs: GO:0009387
Definition: Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA. Source: GOC:mah, PMID:8811192
Comment: None
History: See term history for GO:0003916 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to DNA topoisomerase activity (excluding "regulates").; Link to all direct and indirect annotations to DNA topoisomerase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for DNA topoisomerase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0140097 catalytic activity, acting on DNA
GO:0016853 isomerase activity
GO:0003916 DNA topoisomerase activity
GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0160097 reverse gyrase activity

Parents of DNA topoisomerase activity (GO:0003916)

subject	relation	object
DNA topoisomerase activity	BFO:0000051	DNA binding (GO:0003677)
DNA topoisomerase activity	is_a	isomerase activity (GO:0016853)
DNA topoisomerase activity	is_a	catalytic activity, acting on DNA (GO:0140097)

Children of DNA topoisomerase activity (GO:0003916)

subject	relation	object
DNA topoisomerase type I (single strand cut, ATP-independent) activity (GO:0003917)	is_a	DNA topoisomerase activity
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (GO:0003918)	is_a	DNA topoisomerase activity
reverse gyrase activity (GO:0160097)	is_a	DNA topoisomerase activity

DNA topoisomerase activity