AmiGO 2: Term Details for "GMP reductase activity" (GO:0003920)

Accession: GO:0003920
Name: GMP reductase activity
Ontology: molecular_function
Synonyms: NADPH2:guanosine-5'-phosphate oxidoreductase (deaminating), NADPH:GMP oxidoreductase (deaminating) activity, NADPH:guanosine-5'-phosphate oxidoreductase (deaminating) activity, guanosine 5'-monophosphate oxidoreductase activity, guanosine 5'-monophosphate reductase activity, guanosine 5'-phosphate reductase activity, guanosine monophosphate reductase activity, guanylate reductase activity, inosine-5'-phosphate:NADP+ oxidoreductase (aminating)
Alternate IDs: None
Definition: Catalysis of the reaction: IMP + NADP+ + NH4 = GMP + 2 H+ + NADPH. Source: EC:1.7.1.7, RHEA:17185
Comment: Note that this function was formerly EC:1.6.6.8.
History: See term history for GO:0003920 at QuickGO
Chem. react.: has participant ammonium; has participant hydron; has participant IMP(2-); has participant NADPH(4-); has participant guanosine 5'-monophosphate(2-); has participant NADP(3-)
Subset: None
Related: Link to all genes and gene products annotated to GMP reductase activity (excluding "regulates").; Link to all direct and indirect annotations to GMP reductase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for GMP reductase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
GMP reductase activity	RO:0000057	ammonium (CHEBI:28938)
GMP reductase activity	RO:0000057	hydron (CHEBI:15378)
GMP reductase activity	is_a	oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor (GO:0046857)
GMP reductase activity	RO:0000057	IMP(2-) (CHEBI:58053)
GMP reductase activity	RO:0000057	NADPH(4-) (CHEBI:57783)
GMP reductase activity	RO:0000057	guanosine 5'-monophosphate(2-) (CHEBI:58115)
GMP reductase activity	RO:0000057	NADP(3-) (CHEBI:58349)

subject	relation	object
GMP reductase complex (GO:1902560)	RO:0002215	GMP reductase activity