AmiGO 2: Term Details for "GMP synthase (glutamine-hydrolyzing) activity" (GO:0003922)

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Term Information

Accession: GO:0003922
Name: GMP synthase (glutamine-hydrolyzing) activity
Ontology: molecular_function
Synonyms: GMP synthase (glutamine-hydrolysing), GMP synthetase (glutamine-hydrolysing), GMP synthetase (glutamine-hydrolyzing) activity, glutamine amidotransferase activity, guanosine 5'-monophosphate synthetase activity, guanosine monophosphate synthetase (glutamine-hydrolyzing), guanylate synthetase (glutamine-hydrolyzing), xanthosine 5'-phosphate amidotransferase activity, xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)
Alternate IDs: None
Definition: Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H+. Source: RHEA:11680
Comment: None
History: See term history for GO:0003922 at QuickGO
Chem. react.: has participant diphosphate(3-); has participant L-glutamine zwitterion; has participant hydron; has participant guanosine 5'-monophosphate(2-); has participant 5'-xanthylate(2-); has participant water; has participant L-glutamate(1-); has participant ATP(4-); has participant adenosine 5'-monophosphate(2-)
Subset: None
Related: Link to all genes and gene products annotated to GMP synthase (glutamine-hydrolyzing) activity (excluding "regulates").; Link to all direct and indirect annotations to GMP synthase (glutamine-hydrolyzing) activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for GMP synthase (glutamine-hydrolyzing) activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0044237 cellular metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:0044238 primary metabolic process
GO:0044281 small molecule metabolic process
GO:0009058 biosynthetic process
GO:0055086 nucleobase-containing small molecule metabolic process
GO:1901362 organic cyclic compound biosynthetic process
GO:0071704 organic substance metabolic process
GO:0019637 organophosphate metabolic process
GO:0006796 phosphate-containing compound metabolic process
GO:0006793 phosphorus metabolic process
GO:1901135 carbohydrate derivative metabolic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0006753 nucleoside phosphate metabolic process
GO:1901576 organic substance biosynthetic process
GO:1901564 organonitrogen compound metabolic process
GO:0090407 organophosphate biosynthetic process
GO:1901137 carbohydrate derivative biosynthetic process
GO:0003674 molecular_function
GO:0009123 nucleoside monophosphate metabolic process
GO:1901293 nucleoside phosphate biosynthetic process
GO:0009117 nucleotide metabolic process
GO:1901566 organonitrogen compound biosynthetic process
GO:0072521 purine-containing compound metabolic process
GO:0019693 ribose phosphate metabolic process
GO:0003824 catalytic activity
GO:0009124 nucleoside monophosphate biosynthetic process
GO:0009165 nucleotide biosynthetic process
GO:0009126 purine nucleoside monophosphate metabolic process
GO:0006163 purine nucleotide metabolic process
GO:0072522 purine-containing compound biosynthetic process
GO:0009161 ribonucleoside monophosphate metabolic process
GO:0009259 ribonucleotide metabolic process
GO:0046390 ribose phosphate biosynthetic process
GO:0016874 ligase activity
GO:0009127 purine nucleoside monophosphate biosynthetic process
GO:0006164 purine nucleotide biosynthetic process
GO:0009167 purine ribonucleoside monophosphate metabolic process
GO:0009150 purine ribonucleotide metabolic process
GO:0009156 ribonucleoside monophosphate biosynthetic process
GO:0009260 ribonucleotide biosynthetic process
GO:0046037 GMP metabolic process
GO:0016879 ligase activity, forming carbon-nitrogen bonds
GO:0009168 purine ribonucleoside monophosphate biosynthetic process
GO:0009152 purine ribonucleotide biosynthetic process
GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor
GO:0006177 GMP biosynthetic process
GO:0003922 GMP synthase (glutamine-hydrolyzing) activity
GO:0003921 GMP synthase activity

Parents of GMP synthase (glutamine-hydrolyzing) activity (GO:0003922)

subject	relation	object
GMP synthase (glutamine-hydrolyzing) activity	RO:0000057	diphosphate(3-) (CHEBI:33019)
GMP synthase (glutamine-hydrolyzing) activity	RO:0000057	L-glutamine zwitterion (CHEBI:58359)
GMP synthase (glutamine-hydrolyzing) activity	BFO:0000050	GMP biosynthetic process (GO:0006177)
GMP synthase (glutamine-hydrolyzing) activity	RO:0000057	hydron (CHEBI:15378)
GMP synthase (glutamine-hydrolyzing) activity	RO:0000057	guanosine 5'-monophosphate(2-) (CHEBI:58115)
GMP synthase (glutamine-hydrolyzing) activity	RO:0000057	5'-xanthylate(2-) (CHEBI:57464)
GMP synthase (glutamine-hydrolyzing) activity	RO:0000057	water (CHEBI:15377)
GMP synthase (glutamine-hydrolyzing) activity	is_a	carbon-nitrogen ligase activity, with glutamine as amido-N-donor (GO:0016884)
GMP synthase (glutamine-hydrolyzing) activity	RO:0000057	L-glutamate(1-) (CHEBI:29985)
GMP synthase (glutamine-hydrolyzing) activity	RO:0000057	ATP(4-) (CHEBI:30616)
GMP synthase (glutamine-hydrolyzing) activity	RO:0000057	adenosine 5'-monophosphate(2-) (CHEBI:456215)

Children of GMP synthase (glutamine-hydrolyzing) activity (GO:0003922)

subject	relation	object
GMP synthase activity (GO:0003921)	BFO:0000050	GMP synthase (glutamine-hydrolyzing) activity

EC: 6.3.5.2
MetaCyc: GMP-SYN-GLUT-RXN
Reactome: R-HSA-73792; R-HSA-9748957
RHEA: 11680
Wikipedia: GMP_synthase_(glutamine-hydrolysing)