Term Information

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Accession
GO:0003924
Name
GTPase activity
Ontology
molecular_function
Synonyms
GTPase activity, coupled, heterotrimeric G-protein GTPase, alpha-subunit, heterotrimeric G-protein GTPase, beta-subunit, heterotrimeric G-protein GTPase, gamma-subunit, ARF small monomeric GTPase activity, RHEB small monomeric GTPase activity, Rab small monomeric GTPase activity, Ran small monomeric GTPase activity, Ras small monomeric GTPase activity, Rho small monomeric GTPase activity, Sar small monomeric GTPase activity, dynamin GTPase activity, heterotrimeric G-protein GTPase activity, protein-synthesizing GTPase activity, protein-synthesizing GTPase activity, elongation, protein-synthesizing GTPase activity, initiation, protein-synthesizing GTPase activity, termination, signal-recognition-particle GTPase activity, small monomeric GTPase activity, tubulin GTPase activity, hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement
Alternate IDs
GO:0061745
Definition
Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. Source: PMID:27218782, PMID:26832457
Comment
None
History
See term history for GO:0003924 at QuickGO
Chem. react.
has participant GTP(4-)
has participant GDP(3-)
has participant hydrogenphosphate
has participant hydron
has participant water
Subset
goslim_chembl
goslim_drosophila
goslim_generic
goslim_yeast
goslim_prokaryote
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of GTPase activity (GO:0003924)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
GTPase activity [RO:0000057 relation] RO:0000057  GTP(4-) (CHEBI:37565)
GTPase activity [RO:0000057 relation] RO:0000057  GDP(3-) (CHEBI:58189)
GTPase activity [RO:0000057 relation] RO:0000057  hydrogenphosphate (CHEBI:43474)
GTPase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
GTPase activity [is_a relation] is_a  ribonucleoside triphosphate phosphatase activity (GO:0017111)
GTPase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
Children of GTPase activity (GO:0003924)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of GTPase activity (GO:0043087) [RO:0002211 relation] RO:0002211  GTPase activity
positive regulation of GTPase activity (GO:0043547) [RO:0002213 relation] RO:0002213  GTPase activity
GTPase regulator activity (GO:0030695) [RO:0002578 relation] RO:0002578  GTPase activity
GTPase complex (GO:1905360) [RO:0002215 relation] RO:0002215  GTPase activity
GTPase-dependent fusogenic activity (GO:0140523) [BFO:0000051 relation] BFO:0000051  GTPase activity
GTPase inhibitor activity (GO:0005095) [RO:0002630 relation] RO:0002630  GTPase activity
GTPase activator activity (GO:0005096) [RO:0002629 relation] RO:0002629  GTPase activity
negative regulation of GTPase activity (GO:0034260) [RO:0002212 relation] RO:0002212  GTPase activity
G protein activity (GO:0003925) [is_a relation] is_a  GTPase activity
GTPase motor activity (GO:0061791) [is_a relation] is_a  GTPase activity